Bade Uckac GENEMAPPERS 2026

Bade Uckac

Bade Uckac is an early career researcher whose work focuses on elucidating the genetic and environmental determinants of chronic overlapping pain conditions, including migraine, fibromyalgia, chronic back pain, and diabetic neuropathy. Her research integrates large-scale genetic, clinical, and demographic datasets to disentangle the complex interplay between genetic, environmental, and lifestyle factors that shape chronic pain susceptibility and treatment response. Her current work examines the pharmacogenomics of antidepressant response in individuals with chronic pain and depression, with a particular emphasis on variation in CYP2C19 and CYP2D6 metabolic pathways. By combining statistical genomics, bioinformatics, and epidemiological approaches, she aims to improve understanding of how genetic diversity contributes to treatment variability and to inform personalized strategies for pain management. Bade holds a Bachelor’s degree in Biological Sciences from the University of Westminster (London, UK) and has research experience at the MRC Epidemiology Unit, University of Cambridge, where she contributed to population-based studies investigating the genetic and metabolic underpinnings of complex diseases as a research assistant. Her research interests include the genetics of complex traits and psychiatric disorders, pharmacogenomics in chronic pain management, mechanisms underlying pain onset and chronification, and the neurostructural and lifestyle factors that influence the overall pain experience.